Alan Pestronk Selected Research

positive allosteric modulator PAM-2

1/2020	Cryptogenic small-fiber neuropathies: Serum autoantibody binding to trisulfated heparan disaccharide and fibroblast growth factor receptor-3.
3/2019	Prevalence of Axonal Sensory Neuropathy With IgM Binding to Trisulfated Heparin Disaccharide in Patients With Fibromyalgia.
9/2017	Clinical and Laboratory Profiles of Idiopathic Small Fiber Neuropathy in Children: Case Series.
6/2012	Clinical and laboratory features of neuropathies with serum IgM binding to TS-HDS.
2/2003	Sensory neuropathy with monoclonal IgM binding to a trisulfated heparin disaccharide.

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Alan Pestronk Research Topics

Disease

17	Muscular Diseases (Myopathy) 05/2024 - 04/2004
10	Amyotrophic Lateral Sclerosis (Lou Gehrig's Disease) 01/2020 - 07/2007
8	Duchenne Muscular Dystrophy (Muscular Dystrophy, Becker) 11/2016 - 07/2005
7	Polyneuropathies (Polyneuropathy) 01/2021 - 06/2002
6	Muscular Dystrophies (Muscular Dystrophy) 01/2023 - 06/2002
6	Glycogen Storage Disease Type II (Pompe's Disease) 01/2019 - 04/2010
5	Neurodegenerative Diseases (Neurodegenerative Disease) 04/2024 - 01/2008
5	Myositis (Idiopathic Inflammatory Myopathies) 01/2021 - 03/2009
5	Inclusion Body Myopathy With Early-Onset Paget Disease And Frontotemporal Dementia 05/2009 - 04/2004
4	Dementia (Dementias) 04/2015 - 04/2004
4	Frontotemporal Dementia (Semantic Dementia) 05/2014 - 04/2004
4	Chronic Inflammatory Demyelinating Polyradiculoneuropathy (CIDP) 12/2013 - 02/2005
3	Mitochondrial Diseases (Mitochondrial Disease) 10/2023 - 11/2013
3	Ophthalmoplegia (External Ophthalmoplegia) 06/2018 - 07/2007
3	Inflammation (Inflammations) 11/2011 - 05/2006
3	Inclusion Body Myositis 11/2011 - 03/2009
3	Motor Neuron Disease (Primary Lateral Sclerosis) 01/2008 - 08/2006
3	Osteitis Deformans (Paget's Disease of Bone) 04/2007 - 04/2004
2	Facioscapulohumeral Muscular Dystrophy 05/2024 - 01/2022
2	Muscle Weakness 04/2024 - 12/2021
2	Polymyositis 01/2021 - 03/2009
2	Necrosis 01/2021 - 12/2014
2	Small Fiber Neuropathy 01/2020 - 04/2015
2	Myasthenia Gravis 01/2020 - 04/2015
2	Paraproteinemias (Monoclonal Gammopathy) 06/2018 - 04/2003
2	Interstitial Lung Diseases (Interstitial Lung Disease) 03/2018 - 08/2015
2	Atrophy 01/2017 - 07/2010
2	Weight Gain 11/2016 - 02/2005
2	Muscle Cramp (Cramp) 04/2016 - 08/2013
2	Exanthema (Rash) 08/2015 - 08/2008
2	Rhabdomyolysis 08/2015 - 01/2015
2	Nonaka type Distal myopathy 04/2015 - 02/2011
2	Nervous System Diseases (Neurological Disorders) 11/2013 - 05/2013
2	Proteostasis Deficiencies 03/2013 - 01/2008
2	Pain (Aches) 06/2012 - 04/2011
2	Dermatomyositis (Dermatopolymyositis) 11/2011 - 07/2010
2	Disease Progression 08/2011 - 03/2009
2	Alzheimer Disease (Alzheimer's Disease) 10/2010 - 12/2006
2	Dmd-Associated Dilated Cardiomyopathy 12/2009 - 12/2009
2	Limb-Girdle Muscular Dystrophies (Limb-Girdle Muscular Dystrophy) 11/2009 - 05/2008
2	Waldenstrom Macroglobulinemia (Macroglobulinemia) 04/2003 - 04/2003
1	Surgical Wound Infection 05/2024
1	Poisoning 05/2024
1	Dysferlinopathy 01/2023
1	Leukocytosis (Pleocytosis) 01/2020
1	Immune System Diseases (Immune Disorders) 01/2020
1	Embolism (Embolus) 01/2020
1	Respiratory Insufficiency (Respiratory Failure) 01/2020
1	Fibromyalgia (Fibrositis) 03/2019
1	Arthritis (Polyarthritis) 03/2018

Drug/Important Bio-Agent (IBA)

17	Proteins (Proteins, Gene)FDA Link 04/2015 - 01/2006
8	AntibodiesIBA 01/2021 - 06/2002
7	Immunoglobulin M (IgM)IBA 03/2019 - 06/2002
5	coenzyme Q10 (CoQ10)IBA 10/2023 - 08/2009
5	Adrenal Cortex Hormones (Corticosteroids)IBA 01/2021 - 06/2002
5	positive allosteric modulator PAM-2IBA 01/2020 - 02/2003
5	EnzymesIBA 01/2017 - 03/2009
5	DystrophinIBA 08/2015 - 12/2009
5	Valosin Containing ProteinIBA 05/2009 - 04/2004
4	DisaccharidesIBA 01/2020 - 02/2003
4	human GAA protein (Myozyme)FDA Link 01/2019 - 04/2010
4	AcidsIBA 01/2019 - 04/2010
4	GlycogenIBA 01/2016 - 06/2006
3	DNA-Binding Proteins (DNA Binding Protein)IBA 04/2024 - 01/2008
3	Creatine Kinase (Creatine Phosphokinase)IBA 12/2021 - 08/2015
3	AutoantibodiesIBA 01/2021 - 03/2018
3	Complement System Proteins (Complement)IBA 01/2021 - 06/2002
3	CreatineIBA 01/2020 - 07/2005
3	UbiquitinIBA 06/2006 - 04/2004
2	RNA-Binding Proteins (RNA-Binding Protein)IBA 04/2024 - 03/2013
2	Biomarkers (Surrogate Marker)IBA 01/2023 - 10/2010
2	MyostatinIBA 01/2023 - 05/2008
2	Methylprednisolone FDA LinkGeneric 01/2021 - 02/2005
2	Complement Membrane Attack Complex (Membrane Attack Complex)IBA 01/2021 - 05/2006
2	Cholinergic ReceptorsIBA 01/2020 - 04/2015
2	GlucosidasesIBA 01/2019 - 11/2012
2	Immunoglobulin G (IgG)IBA 09/2017 - 06/2002
2	Prednisone (Sone)FDA LinkGeneric 11/2016 - 02/2005
2	DNA (Deoxyribonucleic Acid)IBA 04/2015 - 04/2015
2	Ceftriaxone (Ceftriaxon)FDA LinkGeneric 10/2014 - 01/2013
2	Carrier Proteins (Binding Protein)IBA 04/2013 - 04/2010
2	SteroidsIBA 08/2011 - 03/2009
2	Ubiquitinated ProteinsIBA 04/2007 - 01/2006
2	Immunoglobulins (Immunoglobulin)IBA 04/2003 - 06/2002
1	6- (5- ((cyclopropylamino)carbonyl)- 3- fluoro- 2- methylphenyl)- N- (2,2- dimethylprpyl)- 3- pyridinecarboxamideIBA 05/2024
1	Transcription Factors (Transcription Factor)IBA 05/2024
1	Doxycycline (Periostat)FDA LinkGeneric 04/2024
1	ubiquinone 7IBA 10/2023
1	FollistatinIBA 01/2023
1	5'-Nucleotidase (5' Nucleotidase)IBA 01/2021
1	Hydroxymethylglutaryl CoA Reductases (HMG CoA Reductase)IBA 01/2021
1	tofersenIBA 01/2020
1	Tamoxifen FDA LinkGeneric 01/2020
1	Fructose-Bisphosphate Aldolase (Aldolase)IBA 01/2020
1	Fibroblast Growth Factors (Fibroblast Growth Factor)IBA 01/2020
1	trisulfated-heparin-disaccharideIBA 03/2019
1	cold agglutininsIBA 06/2018

Therapy/Procedure

9	Therapeutics 01/2022 - 06/2002
3	Denervation 01/2017 - 07/2007
1	Enzyme Replacement Therapy 01/2019